Receptor Grade IGF-1 LR3 (Insulin-like Growth Factor-1 Long R3) is a lab-engineered peptide used exclusively in research settings. It is a modified version of natural IGF-1, with a longer half-life (over 20 hours) due to the substitution of arginine at position 3 and a 13-amino-acid extension. This structural change enhances its stability and bioavailability in test subjects.
In non-human laboratory models, Receptor Grade IGF-1 LR3 is observed to promote accelerated cellular repair, increased protein synthesis, and heightened nutrient transport. It mimics insulin in certain ways but is significantly more potent in supporting cellular growth and recovery in muscle and nerve tissues. Researchers have also noted enhanced satellite cell activation, which may contribute to increased tissue regeneration.
Its effects are dose-dependent and highly sensitive to environmental conditions, making it a valuable compound for studying growth signaling pathways, anabolic activity, and systemic response to synthetic growth factors in test animals. IGF-1 LR3 binds to IGF-1 receptors with high affinity but does not interact with IGF binding proteins as strongly as native IGF-1, allowing for greater free circulation in the system during experimentation.
Summary of Characteristics
| Characteristic | Details |
|---|---|
| Chemical Sequence | MFPAMPLSSL FVNGPRTLCG AELVDALQFV CGDRGFYFNK PTGYGSSSRR APQTGIVDEC CFRSCDLRRL EMYCAPLKPA KSA |
| CAS Number | 143045-27-6 |
| Molecular Formula | C400H625N111O115S9 |
| Molecular Weight | 9117.60 g/mol |
| Other Known Titles | Long R3 IGF-1, IGF-1 Long Arg3, Insulin-like Growth Factor-1 Long R3 |
