Melanotan-2 (MT-2) is a synthetic peptide analog of alpha-melanocyte-stimulating hormone (α-MSH) and is structurally related to endogenous melanocortin peptides referenced in scientific literature. In laboratory research contexts, MT-2 is examined for its molecular structure, receptor-binding affinity, and interaction profiles within the melanocortin receptor family under controlled experimental conditions.
Within non-human experimental systems, MT-2 is frequently utilized in receptor characterization studies to evaluate peptide–receptor interactions involving melanocortin receptors, including MC1R, MC3R, and MC4R. These investigations focus on binding behavior, signaling pathway engagement, and comparative receptor selectivity, without implying physiological outcomes or applications.
In laboratory environments, MT-2 serves as a reference compound for studying melanocortin signaling frameworks, peptide–receptor dynamics, and structure–activity relationships within peptide research models. All use is confined to analytical, in vitro, and non-human research settings conducted by qualified professionals.
This material is supplied strictly for laboratory research purposes only and is not intended for human use, animal use, diagnostic use, or therapeutic application.
Summary of Characteristics
| Characteristic | Details |
|---|---|
| Chemical Sequence of Amino Acids | Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2 |
| CAS Number | 121062-08-6 |
| Molecular Formula | C50H69N15O9 |
| Molecular Weight | 1024.18 g/mol |
| Other Known Titles | MT-2, Melanotan-II, MT-II |





